Natural Products Chemistry

Triterpenoids Characterization with Antioxidant activity from the Aerial Part of Deinbollia pinnata

Abstract

Deinbollia pinnata is a tropical and sub-tropical continental plant widely used by hunters for traditional medicine. It contains large constituents of triterpenoids from which seven (7) known triterpenes for the first time reported using combined chromatographic separation. These include squalene (1) stigmasterol (2), stigmasta-5,22-diene-3-ol acetate (3), ?-sitosterol (4), lupeol (5), taraxasterol (6), and betulinic acid (7) from aerial parts. Their structures were elucidated using HR-ESIMS, 1D NMR compared with existing data. Methanolic leave extracts showed a very high antioxidant potential of minimum inhibitory concentration for DPPH, 22.07 µg/mL; ABTS, 15.40 µg/mL; FRAP, 3.45 ± 1.30 mM. Stigmasta-5,22-diene-3-ol acetate (3) and betulinic acid (7) showed strong to moderate activity as an anti-oxidant reducing agent. These can be in the management of oxidative causative diseases.